Disease: Metastatic malignant neoplasm to brain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DDX53 Q86TM3 DEAD-box helicase 53 0.66 0.568 0.846
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692
TOP1 P11387 DNA topoisomerase I Enzyme 1.00 0.542 0.692
FOXA1 P55317 forkhead box A1 Transcription factor 0.22 0.522 0.731
HK2 P52789 hexokinase 2 Kinase 4.6E-03 0.515 0.769
LILRB1 Q8NHL6 leukocyte immunoglobulin like receptor B1 Receptor 5.7E-14 0.510 0.769
MAP1LC3B Q9GZQ8 microtubule associated protein 1 light chain 3 beta Cellular structure 1.9E-03 0.506 0.846
EPHA2 P29317 EPH receptor A2 Kinase 1.1E-05 0.501 0.731
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846
MIR143 microRNA 143 0.462 0.885
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
CXCR3 P49682 C-X-C motif chemokine receptor 3 G-protein coupled receptor 0.18 0.436 0.808
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
PAEP P09466 progestagen associated endometrial protein Enzyme 3.1E-08 0.430 0.846
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
CD68 P34810 CD68 molecule Transporter 1.4E-06 0.408 0.808
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885