Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
TBX3 O15119 T-box transcription factor 3 Transcription factor 0.99 0.525 0.769