Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
NGF | P01138 | nerve growth factor | Signaling | 0.82 | 0.391 | 0.885 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
CRK | P46108 | CRK proto-oncogene, adaptor protein | 0.96 | 0.394 | 0.923 | |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
SERPINA1 | P01009 | serpin family A member 1 | Enzyme modulator | 6.8E-08 | 0.410 | 0.923 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
SYT1 | P21579 | synaptotagmin 1 | Transporter | 0.60 | 0.412 | 0.846 |
ANGPT2 | O15123 | angiopoietin 2 | Signaling | 0.83 | 0.410 | 0.846 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 |