Disease: Hereditary Nonpolyposis Colorectal Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AIP O00170 aryl hydrocarbon receptor interacting protein Chaperone 0.36 0.517 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EMB Q6PCB8 embigin Receptor 1.0E-11 0.633 0.615
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
FAP Q12884 fibroblast activation protein alpha Enzyme 1.9E-28 0.496 0.808
GSTK1 Q9Y2Q3 glutathione S-transferase kappa 1 1.9E-06 0.412 0.885
HDAC2 Q92769 histone deacetylase 2 Epigenetic regulator 1.00 0.476 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MIR23B microRNA 23b 0.523 0.808
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MYH14 Q7Z406 myosin heavy chain 14 4.2E-02 0.663 0.577
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885