Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAP3K1 Q13233 mitogen-activated protein kinase kinase kinase 1 Kinase 1.00 0.538 0.731
MIR4435-2HG MIR4435-2 host gene 0.604 0.692
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MLLT10 P55197 MLLT10 histone lysine methyltransferase DOT1L cofactor Transcription factor 1.00 0.551 0.462
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MTX1 Q13505 metaxin 1 1.3E-02 0.546 0.731
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
NEK10 Q6ZWH5 NIMA related kinase 10 Kinase 7.7E-10 0.705 0.269
OPCML Q14982 opioid binding protein/cell adhesion molecule like 0.23 0.606 0.654
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PVT1 Pvt1 oncogene 0.495 0.731
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385
RALY Q9UKM9 RALY heterogeneous nuclear ribonucleoprotein 0.14 0.656 0.385
RNF43 Q68DV7 ring finger protein 43 0.73 0.584 0.577
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846