Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
MAP3K1 | Q13233 | mitogen-activated protein kinase kinase kinase 1 | Kinase | 1.00 | 0.538 | 0.731 |
MIR4435-2HG | MIR4435-2 host gene | 0.604 | 0.692 | |||
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MLLT10 | P55197 | MLLT10 histone lysine methyltransferase DOT1L cofactor | Transcription factor | 1.00 | 0.551 | 0.462 |
MRE11 | P49959 | MRE11 homolog, double strand break repair nuclease | 1.3E-12 | 0.527 | 0.808 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
MTX1 | Q13505 | metaxin 1 | 1.3E-02 | 0.546 | 0.731 | |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
NEK10 | Q6ZWH5 | NIMA related kinase 10 | Kinase | 7.7E-10 | 0.705 | 0.269 |
OPCML | Q14982 | opioid binding protein/cell adhesion molecule like | 0.23 | 0.606 | 0.654 | |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PVT1 | Pvt1 oncogene | 0.495 | 0.731 | |||
RAD50 | Q92878 | RAD50 double strand break repair protein | 3.4E-27 | 0.556 | 0.808 | |
RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
RAD51B | O15315 | RAD51 paralog B | 2.1E-15 | 0.556 | 0.769 | |
RAD51C | O43502 | RAD51 paralog C | 6.2E-14 | 0.533 | 0.692 | |
RAD51D | O75771 | RAD51 paralog D | 1.1E-09 | 0.674 | 0.385 | |
RALY | Q9UKM9 | RALY heterogeneous nuclear ribonucleoprotein | 0.14 | 0.656 | 0.385 | |
RNF43 | Q68DV7 | ring finger protein 43 | 0.73 | 0.584 | 0.577 | |
SH2B3 | Q9UQQ2 | SH2B adaptor protein 3 | 1.0E-04 | 0.527 | 0.692 | |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |