Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LMNA P02545 lamin A/C 1.00 0.384 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
KCNH1 O95259 potassium voltage-gated channel subfamily H member 1 Ion channel 0.55 0.542 0.731