Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
VCP P55072 valosin containing protein 1.00 0.469 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808
YY1 P25490 YY1 transcription factor Transcription factor 0.99 0.481 0.808
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
ENTPD1 P49961 ectonucleoside triphosphate diphosphohydrolase 1 Enzyme 8.1E-03 0.499 0.769