Disease: insulinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BTC P35070 betacellulin Signaling 6.2E-02 0.644 0.577
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808
G6PC2 Q9NQR9 glucose-6-phosphatase catalytic subunit 2 3.0E-16 0.751 0.231
GCG P01275 glucagon 3.5E-02 0.431 0.885
GCK P35557 glucokinase Kinase 0.63 0.523 0.808
GIP P09681 gastric inhibitory polypeptide 0.27 0.570 0.654
GLP1R P43220 glucagon like peptide 1 receptor G-protein coupled receptor 0.29 0.471 0.846
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808
IAPP P10997 islet amyloid polypeptide Signaling 3.2E-03 0.507 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
INS P01308 insulin 0.30 0.445 0.923
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
KRT16 P08779 keratin 16 1.5E-14 0.565 0.769
LEP P41159 leptin 0.46 0.349 0.846
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
PAX6 P26367 paired box 6 1.00 0.450 0.769
PCSK1 P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 2.7E-09 0.548 0.615
PDX1 P52945 pancreatic and duodenal homeobox 1 1.8E-02 0.530 0.654
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885