Disease: Presenile dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
UBB P0CG47 ubiquitin B Nucleic acid binding 1.7E-02 0.599 0.615
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TYROBP O43914 transmembrane immune signaling adaptor TYROBP 0.20 0.573 0.769
TSPO P30536 translocator protein 2.7E-04 0.444 0.885
TFEB P19484 transcription factor EB 0.90 0.527 0.731
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
STXBP3 O00186 syntaxin binding protein 3 Transporter 5.2E-05 0.610 0.769
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
SMARCA1 P28370 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 Enzyme 1.00 0.504 0.808
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SET Q01105 SET nuclear proto-oncogene Enzyme modulator 1.00 0.507 0.808
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
STH Q8IWL8 saitohin 0.705 0.385
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
RIDA P52758 reactive intermediate imine deaminase A homolog 6.8E-02 0.606 0.769
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769