Disease: Presenile dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
BPIFA2 Q96DR5 BPI fold containing family A member 2 8.0E-07 0.608 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP2 P42575 caspase 2 Enzyme 1.5E-03 0.565 0.731
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808