Disease: Alzheimer Disease, Late Onset
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CETN1 Q12798 centrin 1 Calcium-binding protein 0.22 0.584 0.654
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
HSPA1A P0DMV8 P0DMV9 heat shock protein family A (Hsp70) member 1A 3.0E-02 0.486 0.769
HSPA1B P0DMV8 P0DMV9 heat shock protein family A (Hsp70) member 1B 5.3E-03 0.474 0.808
IAPP P10997 islet amyloid polypeptide Signaling 3.2E-03 0.507 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885