Disease: Mitochondrial Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RARS2 Q5T160 arginyl-tRNA synthetase 2, mitochondrial 7.7E-14 0.663 0.462
DGUOK Q16854 deoxyguanosine kinase Kinase 3.7E-07 0.593 0.500
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
ELAC2 Q9BQ52 elaC ribonuclease Z 2 1.7E-20 0.670 0.346
FBXL4 Q9UKA2 F-box and leucine rich repeat protein 4 1.1E-08 0.695 0.423
FOXRED1 Q96CU9 FAD dependent oxidoreductase domain containing 1 Enzyme 2.0E-16 0.633 0.462
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808
GFER P55789 growth factor, augmenter of liver regeneration Enzyme 1.7E-04 0.560 0.846
MGME1 Q9BQP7 mitochondrial genome maintenance exonuclease 1 1.8E-03 0.695 0.423
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
MTO1 Q9Y2Z2 mitochondrial tRNA translation optimization 1 7.4E-06 0.670 0.462
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NOL3 O60936 nucleolar protein 3 2.0E-04 0.575 0.808
NUBPL Q8TB37 nucleotide binding protein like 1.1E-05 0.670 0.423
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
SARDH Q9UL12 sarcosine dehydrogenase Enzyme 5.3E-16 0.523 0.846
SDS P20132 serine dehydratase Enzyme 1.4E-04 0.534 0.769
SORD Q00796 sorbitol dehydrogenase Enzyme 4.5E-08 0.552 0.769
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923