Disease: Tonic - clonic seizures
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808
ALDH7A1 P49419 aldehyde dehydrogenase 7 family member A1 Enzyme 1.4E-22 0.551 0.769
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CACNA1H O95180 calcium voltage-gated channel subunit alpha1 H Ion channel 4.8E-10 0.628 0.423
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
EFHC1 Q5JVL4 EF-hand domain containing 1 1.9E-17 0.659 0.231
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
GRIA3 P42263 glutamate ionotropic receptor AMPA type subunit 3 Ion channel 1.00 0.566 0.692
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
HNRNPU Q00839 heterogeneous nuclear ribonucleoprotein U 1.00 0.575 0.654
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KCNA1 Q09470 potassium voltage-gated channel subfamily A member 1 Ion channel 7.6E-02 0.573 0.577
LEP P41159 leptin 0.46 0.349 0.846
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIGO Q8TEQ8 phosphatidylinositol glycan anchor biosynthesis class O 6.1E-11 0.636 0.615
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846