Disease: Seizures, Focal
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
FAM20C Q8IXL6 FAM20C golgi associated secretory pathway kinase 0.31 0.578 0.731
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
GRIK2 Q13002 glutamate ionotropic receptor kainate type subunit 2 Ion channel 1.00 0.561 0.769
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KCNT1 Q5JUK3 potassium sodium-activated channel subfamily T member 1 Ion channel 2.8E-05 0.610 0.308
LAMA2 P24043 laminin subunit alpha 2 Enzyme modulator 2.4E-47 0.553 0.692
LEP P41159 leptin 0.46 0.349 0.846
MED23 Q9ULK4 mediator complex subunit 23 3.1E-08 0.612 0.654
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PLCB1 Q9NQ66 phospholipase C beta 1 Enzyme 0.98 0.595 0.654
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
RBFOX1 Q9NWB1 RNA binding fox-1 homolog 1 Nucleic acid binding 0.95 0.584 0.692
REST Q13127 RE1 silencing transcription factor Transcription factor 0.99 0.535 0.808
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808