Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
LMNA P02545 lamin A/C 1.00 0.384 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
HPR P00739 haptoglobin-related protein Enzyme 5.5E-10 0.578 0.615
XCL1 P47992 X-C motif chemokine ligand 1 Signaling 1.3E-03 0.601 0.692
CPM P14384 carboxypeptidase M 1.7E-05 0.682 0.538
BRCA3 breast cancer 3 0.705 0.269
TMEM135 Q86UB9 transmembrane protein 135 0.78 0.751 0.346