Disease: Moderate intellectual disability
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
DMD P11532 dystrophin 1.00 0.423 0.923
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808
USP9X Q93008 ubiquitin specific peptidase 9 X-linked 1.00 0.502 0.846
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
SMARCA2 P51531 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Epigenetic regulator 1.00 0.527 0.769
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615
CUL4B Q13620 cullin 4B Enzyme 1.00 0.556 0.769
ACSL4 O60488 acyl-CoA synthetase long chain family member 4 Enzyme 0.98 0.561 0.769
GRIA3 P42263 glutamate ionotropic receptor AMPA type subunit 3 Ion channel 1.00 0.566 0.692
PAK3 O75914 p21 (RAC1) activated kinase 3 Kinase 0.99 0.569 0.731
GDI1 P31150 GDP dissociation inhibitor 1 Enzyme 0.99 0.572 0.654
IQSEC2 Q5JU85 IQ motif and Sec7 domain ArfGEF 2 1.00 0.573 0.577
CLCN4 P51793 chloride voltage-gated channel 4 Ion channel 1.00 0.587 0.654
SYN1 P17600 synapsin I Cellular structure 0.99 0.597 0.462