Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
MLLT10 P55197 MLLT10 histone lysine methyltransferase DOT1L cofactor Transcription factor 1.00 0.551 0.462
PTCH2 Q9Y6C5 patched 2 3.4E-16 0.563 0.692
HOXB13 Q92826 homeobox B13 3.7E-08 0.573 0.462
INTS2 Q9H0H0 integrator complex subunit 2 1.00 0.590 0.654
BNC2 Q6ZN30 basonuclin 2 Nucleic acid binding 0.93 0.612 0.615
HAGLR HOXD antisense growth-associated long non-coding RNA 0.619 0.385