Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962