Source: CLINVAR ×
| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| B2M | P61769 | beta-2-microglobulin | Immune response | 0.56 | 0.447 | 0.846 |
| BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
| CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
| CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
| EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
| ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
| FBXW7 | Q969H0 | F-box and WD repeat domain containing 7 | Enzyme modulator | 1.00 | 0.465 | 0.808 |
| FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
| GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
| HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
| MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
| NFE2L2 | Q16236 | nuclear factor, erythroid 2 like 2 | Enzyme | 3.6E-03 | 0.357 | 0.885 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| PPP2R1A | P30153 | protein phosphatase 2 scaffold subunit Aalpha | Enzyme | 0.98 | 0.588 | 0.577 |
| RHOA | P61586 | ras homolog family member A | Enzyme modulator | 0.60 | 0.502 | 0.808 |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
| U2AF1 | P0DN76 Q01081 | U2 small nuclear RNA auxiliary factor 1 | Nucleic acid binding | 0.99 | 0.604 | 0.577 |