Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
ENG P17813 endoglin 1.00 0.446 0.846
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
GAST P01350 gastrin 2.7E-03 0.485 0.808
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808