Disease: Invasive carcinoma of breast
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR146A microRNA 146a 0.398 0.885
MIR200C microRNA 200c 0.486 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
APOBEC3B Q9UH17 apolipoprotein B mRNA editing enzyme catalytic subunit 3B Enzyme 5.2E-16 0.547 0.731
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
ELP3 Q9H9T3 elongator acetyltransferase complex subunit 3 Enzyme 3.0E-14 0.751 0.231
HRG P04196 histidine rich glycoprotein Enzyme modulator 5.9E-14 0.603 0.577
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
GRB7 Q14451 growth factor receptor bound protein 7 Receptor 1.4E-06 0.603 0.462
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846