Disease: Adolescent idiopathic scoliosis
Source: GWASCAT ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EIF4G3 O43432 eukaryotic translation initiation factor 4 gamma 3 Nucleic acid binding 1.00 0.780 0.308
PLCL2 Q9UPR0 phospholipase C like 2 Enzyme 1.00 0.743 0.308
AFF3 P51826 AF4/FMR2 family member 3 Transcription factor 1.00 0.623 0.692
SOX6 P35712 SRY-box transcription factor 6 1.00 0.578 0.615
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
TLE1 Q04724 TLE family member 1, transcriptional corepressor Transcription factor 1.00 0.560 0.654
MYO16 Q9Y6X6 myosin XVI 1.00 0.722 0.308
DENND4A Q7Z401 DENN domain containing 4A 1.00 0.821 0.192
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PDE4B Q07343 phosphodiesterase 4B 0.47 0.566 0.731
NPRL3 Q12980 NPR3 like, GATOR1 complex subunit 0.19 0.678 0.385
CBFA2T3 O75081 CBFA2/RUNX1 partner transcriptional co-repressor 3 Transcription factor 4.8E-02 0.638 0.462
CERS6 Q6ZMG9 ceramide synthase 6 3.9E-02 0.650 0.615
PLCL1 Q15111 phospholipase C like 1 (inactive) Enzyme 1.2E-02 0.608 0.654
NREP Q16612 neuronal regeneration related protein 5.6E-03 0.682 0.577
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
ALDH1L1 O75891 aldehyde dehydrogenase 1 family member L1 Enzyme 1.4E-11 0.663 0.615
DEPTOR Q8TB45 DEP domain containing MTOR interacting protein Enzyme modulator 3.7E-12 0.626 0.654
ME3 Q16798 malic enzyme 3 Enzyme 1.5E-13 0.792 0.192
ACOXL Q9NUZ1 acyl-CoA oxidase like Enzyme 5.2E-15 0.674 0.577
AK9 Q5TCS8 adenylate kinase 9 Kinase 3.7E-26 0.751 0.346
NBEAL1 Q6ZS30 neurobeachin like 1 5.1E-33 0.638 0.692
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885