Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
NLRP3 | Q96P20 | NLR family pyrin domain containing 3 | 8.1E-04 | 0.361 | 0.962 | |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
HMGB1 | P09429 | high mobility group box 1 | Nucleic acid binding | 0.82 | 0.368 | 0.923 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
IL1RN | P18510 | interleukin 1 receptor antagonist | 3.1E-02 | 0.373 | 0.923 | |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
STAT1 | P42224 | signal transducer and activator of transcription 1 | Nucleic acid binding | 1.00 | 0.399 | 0.885 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
ISG20 | Q96AZ6 | interferon stimulated exonuclease gene 20 | 2.9E-03 | 0.414 | 0.846 | |
TYMS | P04818 | thymidylate synthetase | Enzyme | 0.72 | 0.425 | 0.846 |
ABO | P16442 | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | Enzyme | 0.427 | 0.885 | |
MCL1 | Q07820 | MCL1 apoptosis regulator, BCL2 family member | Signaling | 0.96 | 0.430 | 0.808 |
FOXO3 | O43524 | forkhead box O3 | 0.99 | 0.431 | 0.808 | |
FOXO1 | Q12778 | forkhead box O1 | 1.00 | 0.433 | 0.846 | |
FOXM1 | Q08050 | forkhead box M1 | 7.4E-04 | 0.441 | 0.769 | |
F2R | P25116 | coagulation factor II thrombin receptor | G-protein coupled receptor | 8.5E-03 | 0.444 | 0.846 |
ABCC1 | P33527 | ATP binding cassette subfamily C member 1 | Transporter | 1.2E-03 | 0.445 | 0.808 |
ANGPT1 | Q15389 | angiopoietin 1 | Signaling | 0.95 | 0.446 | 0.808 |
PRKAA1 | Q13131 | protein kinase AMP-activated catalytic subunit alpha 1 | Kinase | 0.14 | 0.453 | 0.846 |