Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
CDH1 P12830 cadherin 1 0.15 0.401 0.808
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
ISG20 Q96AZ6 interferon stimulated exonuclease gene 20 2.9E-03 0.414 0.846
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808