Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692
NFIX Q14938 nuclear factor I X Nucleic acid binding 1.00 0.547 0.769
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808
TPM3 P06753 tropomyosin 3 Cellular structure 6.7E-03 0.490 0.808
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
NEB P20929 nebulin 4.6E-41 0.608 0.692
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
RFWD3 Q6PCD5 ring finger and WD repeat domain 3 Enzyme 3.5E-10 0.569 0.731
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 1.00 0.592 0.731