Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
INS P01308 insulin 0.30 0.445 0.923
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
NEFL P07196 neurofilament light 0.488 0.769
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
ASCC1 Q8N9N2 activating signal cointegrator 1 complex subunit 1 2.6E-14 0.495 0.846
MPZ P25189 myelin protein zero 0.27 0.503 0.846
SERPING1 P05155 serpin family G member 1 Enzyme modulator 0.96 0.507 0.769
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808