Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
TBCE Q15813 tubulin folding cofactor E Chaperone 1.7E-08 0.575 0.692
SLC25A4 P12235 solute carrier family 25 member 4 Transporter 0.45 0.568 0.692
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
GCK P35557 glucokinase Kinase 0.63 0.523 0.808
POLG2 Q9UHN1 DNA polymerase gamma 2, accessory subunit Enzyme 1.5E-10 0.558 0.769
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
PNPLA6 Q8IY17 patatin like phospholipase domain containing 6 Enzyme 1.9E-13 0.533 0.769
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
GLE1 Q53GS7 GLE1 RNA export mediator Transporter 2.1E-10 0.628 0.577
MPZ P25189 myelin protein zero 0.27 0.503 0.846
INS P01308 insulin 0.30 0.445 0.923
PDX1 P52945 pancreatic and duodenal homeobox 1 1.8E-02 0.530 0.654