Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
INS P01308 insulin 0.30 0.445 0.923
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NEFL P07196 neurofilament light 0.488 0.769
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808