Disease: Spastic Paraplegia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
AMPD2 Q01433 adenosine monophosphate deaminase 2 Enzyme 4.5E-07 0.663 0.577
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654
C12orf65 Q9H3J6 chromosome 12 open reading frame 65 Nucleic acid binding 0.21 0.678 0.346
CCT5 P48643 chaperonin containing TCP1 subunit 5 Chaperone 1.00 0.663 0.462
CYP2U1 Q7Z449 cytochrome P450 family 2 subfamily U member 1 1.4E-03 0.722 0.462
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GBE1 Q04446 1,4-alpha-glucan branching enzyme 1 Enzyme 1.1E-12 0.612 0.654
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
KLC2 Q9H0B6 kinesin light chain 2 0.98 0.736 0.346
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769
PNPLA6 Q8IY17 patatin like phospholipase domain containing 6 Enzyme 1.9E-13 0.533 0.769
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
ZFYVE26 Q68DK2 zinc finger FYVE-type containing 26 4.7E-23 0.636 0.615