Disease: Hereditary Motor and Sensory-Neuropathy Type II
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
LMNA P02545 lamin A/C 1.00 0.384 0.885
MAD2L1BP Q15013 MAD2L1 binding protein 1.4E-08 0.623 0.577
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NEFL P07196 neurofilament light 0.488 0.769
RETREG1 Q9H6L5 reticulophagy regulator 1 6.4E-06 0.623 0.538
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
TTR P02766 transthyretin Transporter 0.52 0.423 0.885