Disease: Sensorimotor neuropathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
DARS2 Q6PI48 aspartyl-tRNA synthetase 2, mitochondrial Enzyme 9.8E-13 0.638 0.577
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
HADHB P55084 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta Enzyme 1.5E-11 0.619 0.692
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
IFRD1 O00458 interferon related developmental regulator 1 1.2E-03 0.666 0.462
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
NEFL P07196 neurofilament light 0.488 0.769
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeats 2 8.3E-16 0.666 0.385
SLC12A6 Q9UHW9 solute carrier family 12 member 6 Transporter 1.1E-02 0.603 0.500
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
TDP1 Q9NUW8 tyrosyl-DNA phosphodiesterase 1 Enzyme 1.3E-17 0.612 0.538
TTR P02766 transthyretin Transporter 0.52 0.423 0.885