Disease: Slow progression
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
COA7 Q96BR5 cytochrome c oxidase assembly factor 7 (putative) 6.0E-02 0.792 0.231
DARS2 Q6PI48 aspartyl-tRNA synthetase 2, mitochondrial Enzyme 9.8E-13 0.638 0.577
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GBE1 Q04446 1,4-alpha-glucan branching enzyme 1 Enzyme 1.1E-12 0.612 0.654
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
MARS1 P56192 methionyl-tRNA synthetase 1 2.1E-15 0.638 0.654
MCM3AP O60318 minichromosome maintenance complex component 3 associated protein 5.2E-09 0.647 0.654
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MTMR14 Q8NCE2 myotubularin related protein 14 1.4E-07 0.674 0.615
NEFL P07196 neurofilament light 0.488 0.769
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769
RETREG1 Q9H6L5 reticulophagy regulator 1 6.4E-06 0.623 0.538
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SLC25A4 P12235 solute carrier family 25 member 4 Transporter 0.45 0.568 0.692