Disease: Alzheimer disease, familial, type 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
ALB P02768 albumin Transporter 0.64 0.317 0.962
AKR1C4 P17516 aldo-keto reductase family 1 member C4 Enzyme 2.2E-17 0.587 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808
CLU P10909 clusterin 7.8E-05 0.426 0.885
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885