Disease: secondary acute myeloid leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
PRSS27 Q9BQR3 serine protease 27 Enzyme 8.0E-05 0.805 0.154
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
AURKB Q96GD4 aurora kinase B Kinase 4.5E-03 0.510 0.769
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CSF3R Q99062 colony stimulating factor 3 receptor Signaling 1.5E-10 0.550 0.692
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
JARID2 Q92833 jumonji and AT-rich interaction domain containing 2 Transcription factor 1.00 0.615 0.577
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IKZF1 Q13422 IKAROS family zinc finger 1 Transcription factor 1.00 0.533 0.769
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885