Disease: secondary acute myeloid leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
IKZF1 Q13422 IKAROS family zinc finger 1 Transcription factor 1.00 0.533 0.769
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
INPP5D Q92835 inositol polyphosphate-5-phosphatase D 0.97 0.558 0.731
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
JARID2 Q92833 jumonji and AT-rich interaction domain containing 2 Transcription factor 1.00 0.615 0.577
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PRSS27 Q9BQR3 serine protease 27 Enzyme 8.0E-05 0.805 0.154
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
RARS1 P54136 arginyl-tRNA synthetase 1 3.3E-08 0.604 0.538
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SCT P09683 secretin 1.4E-07 0.484 0.846
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
THPO P40225 thrombopoietin 0.20 0.513 0.692
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923