Disease: Thrombocythemia, Essential
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CD177 Q8N6Q3 CD177 molecule 0.595 0.654
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CD69 Q07108 CD69 molecule 3.0E-02 0.488 0.923
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
CISH Q9NSE2 cytokine inducible SH2 containing protein Enzyme modulator 5.4E-04 0.500 0.808
CNTNAP1 P78357 contactin associated protein 1 3.4E-05 0.554 0.577
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CSF3R Q99062 colony stimulating factor 3 receptor Signaling 1.5E-10 0.550 0.692
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
DKK3 Q9UBP4 dickkopf WNT signaling pathway inhibitor 3 4.1E-06 0.500 0.731
EPO P01588 erythropoietin 1.1E-02 0.381 0.885