Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
RAC1 | P63000 | Rac family small GTPase 1 | Enzyme modulator | 0.76 | 0.429 | 0.962 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
BRD4 | O60885 | bromodomain containing 4 | Epigenetic regulator | 1.00 | 0.446 | 0.885 |
FTO | Q9C0B1 | FTO alpha-ketoglutarate dependent dioxygenase | 8.4E-08 | 0.486 | 0.885 | |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
INSR | P06213 | insulin receptor | Kinase | 3.6E-05 | 0.432 | 0.846 |
HNF1A | P20823 | HNF1 homeobox A | Nucleic acid binding | 0.96 | 0.478 | 0.846 |
NT5C2 | P49902 | 5'-nucleotidase, cytosolic II | Enzyme | 2.1E-06 | 0.537 | 0.846 |
SMOC1 | Q9H4F8 | SPARC related modular calcium binding 1 | Calcium-binding protein | 9.5E-03 | 0.565 | 0.846 |
FBN2 | P35556 | fibrillin 2 | Calcium-binding protein | 1.00 | 0.505 | 0.808 |
PTK2 | Q05397 | protein tyrosine kinase 2 | Kinase | 1.00 | 0.497 | 0.808 |
SKI | P12755 | SKI proto-oncogene | 1.00 | 0.503 | 0.808 | |
FADS1 | O60427 | fatty acid desaturase 1 | 0.37 | 0.582 | 0.769 | |
PEPD | P12955 | peptidase D | Enzyme | 1.5E-14 | 0.621 | 0.769 |
SLC39A8 | Q9C0K1 | solute carrier family 39 member 8 | Transporter | 0.67 | 0.584 | 0.769 |
MECOM | Q03112 | MDS1 and EVI1 complex locus | 1.00 | 0.513 | 0.731 | |
RAPSN | Q13702 | receptor associated protein of the synapse | 1.5E-03 | 0.593 | 0.731 | |
PKD2L1 | Q9P0L9 | polycystin 2 like 1, transient receptor potential cation channel | Ion channel | 1.6E-27 | 0.565 | 0.731 |
ZFPM2 | Q8WW38 | zinc finger protein, FOG family member 2 | Transcription factor | 1.00 | 0.565 | 0.731 |
SLC25A37 | Q9NYZ2 | solute carrier family 25 member 37 | Transporter | 0.28 | 0.597 | 0.731 |
KANSL1 | Q7Z3B3 | KAT8 regulatory NSL complex subunit 1 | 1.00 | 0.592 | 0.731 | |
PRKCE | Q02156 | protein kinase C epsilon | Kinase | 1.00 | 0.597 | 0.692 |
FADS2 | O95864 | fatty acid desaturase 2 | 1.00 | 0.575 | 0.692 | |
RTN4 | Q9NQC3 | reticulon 4 | 0.45 | 0.621 | 0.692 |