Disease: Splenomegaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ANK1 P16157 ankyrin 1 1.00 0.540 0.885
AP3B1 O00203 adaptor related protein complex 3 subunit beta 1 Transporter 0.62 0.619 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
EIF2AK1 Q9BQI3 eukaryotic translation initiation factor 2 alpha kinase 1 Kinase 7.0E-07 0.633 0.577
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
GFI1B Q5VTD9 growth factor independent 1B transcriptional repressor 5.2E-04 0.623 0.500
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846
HBB P68871 hemoglobin subunit beta 1.2E-09 0.494 0.808
HBG2 P69892 hemoglobin subunit gamma 2 0.67 0.565 0.692
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HK1 P19367 hexokinase 1 Kinase 0.91 0.542 0.731
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846
LIPA P38571 lipase A, lysosomal acid type Enzyme 5.5E-07 0.564 0.654
LPIN2 Q92539 lipin 2 5.0E-05 0.628 0.615
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MVK Q03426 mevalonate kinase Kinase 0.17 0.576 0.731
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
PEPD P12955 peptidase D Enzyme 1.5E-14 0.621 0.769
PIEZO1 Q92508 piezo type mechanosensitive ion channel component 1 Ion channel 3.9E-21 0.552 0.769
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885