Disease: Acromegaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
FLNA P21333 filamin A 1.00 0.419 0.846
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
LEP P41159 leptin 0.46 0.349 0.846
MIR21 microRNA 21 0.363 0.846
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
SST P61278 somatostatin Signaling 0.34 0.399 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP73 O15350 tumor protein p73 Transcription factor 1.00 0.449 0.808
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923