Disease: Congenital contractural arachnodactyly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
APLN Q9ULZ1 apelin 0.46 0.497 0.769
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCAT2 colon cancer associated transcript 2 0.621 0.615
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
CMA1 P23946 chymase 1 Enzyme 7.6E-09 0.514 0.692
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885