Disease: Malignant transformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 1.00 0.486 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731
AXIN2 Q9Y2T1 axin 2 0.57 0.507 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCL20 P78556 C-C motif chemokine ligand 20 Signaling 2.4E-04 0.474 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
CD40 P25942 CD40 molecule 0.85 0.396 0.846
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769