Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
IL1RN | P18510 | interleukin 1 receptor antagonist | 3.1E-02 | 0.373 | 0.923 | |
HMOX1 | P09601 | heme oxygenase 1 | 9.7E-03 | 0.381 | 0.923 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
KL | Q9UEF7 | klotho | Enzyme | 2.2E-04 | 0.448 | 0.769 |
TH | P07101 | tyrosine hydroxylase | 1.7E-06 | 0.462 | 0.885 | |
SYP | P08247 | synaptophysin | Transporter | 0.92 | 0.481 | 0.808 |
TRH | P20396 | thyrotropin releasing hormone | 8.9E-04 | 0.519 | 0.846 | |
HTR1A | P08908 | 5-hydroxytryptamine receptor 1A | G-protein coupled receptor | 0.20 | 0.522 | 0.846 |
POR | P16435 | cytochrome p450 oxidoreductase | 3.4E-10 | 0.502 | 0.769 | |
SIGMAR1 | Q99720 | sigma non-opioid intracellular receptor 1 | 0.17 | 0.544 | 0.808 | |
CAMKMT | Q7Z624 | calmodulin-lysine N-methyltransferase | 1.4E-15 | 0.510 | 0.808 | |
GRIA1 | P42261 | glutamate ionotropic receptor AMPA type subunit 1 | Ion channel | 1.00 | 0.570 | 0.577 |
HTR7 | P34969 | 5-hydroxytryptamine receptor 7 | G-protein coupled receptor | 4.5E-02 | 0.592 | 0.500 |
PNOC | Q13519 | prepronociceptin | Signaling | 1.5E-02 | 0.603 | 0.577 |
APOD | P05090 | apolipoprotein D | 5.4E-04 | 0.584 | 0.577 |