Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
MTCO2P12 | MT-CO2 pseudogene 12 | 0.368 | 0.962 | |||
KDR | P35968 | kinase insert domain receptor | Kinase | 1.00 | 0.378 | 0.885 |
HPGDS | O60760 | hematopoietic prostaglandin D synthase | 1.8E-06 | 0.388 | 0.923 | |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
PDCD1 | Q15116 | programmed cell death 1 | 0.42 | 0.402 | 0.846 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
SOX9 | P48436 | SRY-box transcription factor 9 | 1.00 | 0.419 | 0.846 | |
INSR | P06213 | insulin receptor | Kinase | 3.6E-05 | 0.432 | 0.846 |
INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | |
HSPA5 | P11021 | heat shock protein family A (Hsp70) member 5 | 0.77 | 0.434 | 0.885 | |
TIMP3 | P35625 | TIMP metallopeptidase inhibitor 3 | Enzyme modulator | 0.63 | 0.445 | 0.923 |
TCF7L2 | Q9NQB0 | transcription factor 7 like 2 | 1.00 | 0.485 | 0.846 | |
PAK1 | Q13153 | p21 (RAC1) activated kinase 1 | Kinase | 1.3E-03 | 0.494 | 0.808 |
NEU1 | Q99519 | neuraminidase 1 | Enzyme | 7.3E-05 | 0.513 | 0.769 |
CDK9 | P50750 | cyclin dependent kinase 9 | Kinase | 8.9E-05 | 0.498 | 0.769 |