Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
NOS1 | P29475 | nitric oxide synthase 1 | 1.00 | 0.408 | 0.885 | |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
NOTCH2 | Q04721 | notch receptor 2 | 1.00 | 0.441 | 0.808 | |
PTPRC | P08575 | protein tyrosine phosphatase receptor type C | Enzyme | 1.00 | 0.435 | 0.808 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
KMT2D | O14686 | lysine methyltransferase 2D | 1.00 | 0.465 | 0.808 | |
DICER1 | Q9UPY3 | dicer 1, ribonuclease III | Enzyme | 1.00 | 0.446 | 0.846 |
HDAC6 | Q9UBN7 | histone deacetylase 6 | Epigenetic regulator | 1.00 | 0.465 | 0.846 |
HDAC4 | P56524 | histone deacetylase 4 | Epigenetic regulator | 1.00 | 0.484 | 0.885 |
NSD1 | Q96L73 | nuclear receptor binding SET domain protein 1 | Epigenetic regulator | 1.00 | 0.505 | 0.769 |
FASN | P49327 | fatty acid synthase | Enzyme | 1.00 | 0.474 | 0.846 |
KMT2B | Q9UMN6 | lysine methyltransferase 2B | 1.00 | 0.529 | 0.808 | |
AGO2 | Q9UKV8 | argonaute RISC catalytic component 2 | 1.00 | 0.501 | 0.885 | |
XPO1 | O14980 | exportin 1 | Receptor | 1.00 | 0.504 | 0.692 |
SLIT2 | O94813 | slit guidance ligand 2 | 1.00 | 0.511 | 0.769 | |
KDM6B | O15054 | lysine demethylase 6B | Epigenetic regulator | 1.00 | 0.514 | 0.808 |
CUL4B | Q13620 | cullin 4B | Enzyme | 1.00 | 0.556 | 0.769 |