Disease: Metastatic melanoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMP7 P18075 bone morphogenetic protein 7 Signaling 0.13 0.498 0.769
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN3 Q16667 cyclin dependent kinase inhibitor 3 1.9E-03 0.514 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DES P17661 desmin 8.8E-03 0.460 0.846
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
EYA1 Q99502 EYA transcriptional coactivator and phosphatase 1 0.95 0.531 0.731
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
FLII Q13045 FLII actin remodeling protein 5.5E-12 0.520 0.808
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846