Disease: keratoacanthoma
Source: BEFREE ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZHX2 Q9Y6X8 zinc fingers and homeoboxes 2 Transcription factor 3.4E-02 0.510 0.654
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
FAP Q12884 fibroblast activation protein alpha Enzyme 1.9E-28 0.496 0.808
REEP5 Q00765 receptor accessory protein 5 Transporter 7.0E-04 0.633 0.615
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923