Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |
ENG | P17813 | endoglin | 1.00 | 0.446 | 0.846 | |
EPHX1 | P07099 | epoxide hydrolase 1 | 3.2E-09 | 0.500 | 0.846 | |
FAP | Q12884 | fibroblast activation protein alpha | Enzyme | 1.9E-28 | 0.496 | 0.808 |
FBXO11 | Q86XK2 | F-box protein 11 | Enzyme | 1.00 | 0.604 | 0.692 |
GREM1 | O60565 | gremlin 1, DAN family BMP antagonist | 0.47 | 0.508 | 0.808 | |
GSTM1 | P09488 | glutathione S-transferase mu 1 | 2.1E-03 | 0.380 | 0.923 | |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
GSTT1 | P30711 | glutathione S-transferase theta 1 | 1.5E-04 | 0.393 | 0.923 | |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MSH3 | P20585 | mutS homolog 3 | Nucleic acid binding | 7.4E-31 | 0.474 | 0.769 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
MUTYH | Q9UIF7 | mutY DNA glycosylase | Enzyme | 1.3E-18 | 0.521 | 0.769 |
NAT1 | P18440 | N-acetyltransferase 1 | Enzyme | 1.9E-14 | 0.536 | 0.846 |
NAT2 | P11245 | N-acetyltransferase 2 | Enzyme | 3.3E-06 | 0.451 | 0.885 |