Disease: Multiple polyps
Source: BEFREE ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
FAP Q12884 fibroblast activation protein alpha Enzyme 1.9E-28 0.496 0.808
GREM1 O60565 gremlin 1, DAN family BMP antagonist 0.47 0.508 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MLH3 Q9UHC1 mutL homolog 3 Nucleic acid binding 4.9E-08 0.582 0.538
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
POLE Q07864 DNA polymerase epsilon, catalytic subunit 8.0E-27 0.526 0.731
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
RNF43 Q68DV7 ring finger protein 43 0.73 0.584 0.577
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808