Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
HOXD3 | P31249 | homeobox D3 | 0.44 | 0.670 | 0.462 | |
EIF6 | P56537 | eukaryotic translation initiation factor 6 | Nucleic acid binding | 0.24 | 0.584 | 0.538 |
TEK | Q02763 | TEK receptor tyrosine kinase | Kinase | 1.00 | 0.462 | 0.692 |
PAX2 | Q02962 | paired box 2 | 0.67 | 0.495 | 0.731 | |
PAX8 | Q06710 | paired box 8 | 1.00 | 0.477 | 0.731 | |
TBX2 | Q13207 | T-box transcription factor 2 | Transcription factor | 0.99 | 0.544 | 0.769 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 | |
NTRK1 | P04629 | neurotrophic receptor tyrosine kinase 1 | Kinase | 2.0E-06 | 0.422 | 0.808 |
SCN1A | P35498 | sodium voltage-gated channel alpha subunit 1 | Ion channel | 1.00 | 0.477 | 0.808 |
HNF1B | P35680 | HNF1 homeobox B | Nucleic acid binding | 1.00 | 0.473 | 0.808 |
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
MIR486-1 | microRNA 486-1 | 0.521 | 0.808 | |||
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
KCNMA1 | Q12791 | potassium calcium-activated channel subfamily M alpha 1 | Ion channel | 1.00 | 0.518 | 0.846 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
ROS1 | P08922 | ROS proto-oncogene 1, receptor tyrosine kinase | Kinase | 1.6E-72 | 0.439 | 0.885 |
TTN | Q8WZ42 | titin | Kinase | 2.6E-96 | 0.470 | 0.885 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |