Disease: Malignant Peripheral Nerve Sheath Tumor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MIR21 microRNA 21 0.363 0.846
MIR30A microRNA 30a 0.478 0.808
MXI1 P50539 MAX interactor 1, dimerization protein Transcription factor 1.1E-03 0.547 0.615
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
PAX8 Q06710 paired box 8 1.00 0.477 0.731
PDCD4 Q53EL6 programmed cell death 4 Nucleic acid binding 3.4E-07 0.494 0.769
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808